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Steroid Responsive Meningitis In Dogs

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Method of glycerol test The patients are advised to report empty stomach on the day of investigation. All these patients were subjected to glycerol testing to determine their suitability for administration of hydrochlorothiazide. Steroids can cause shrinkage of the adrenal glands, leading to adrenal insufficiency.

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Conventional veterinary treatment largely relies on the use of drugs to suppress the immune system and any inflammation. Although this often (not always) provides relief, as we have seen, it also carries the risk of significant and potentially serious side-effects if continued long term. Amounts to be administered and administration routeFor oral administration.The dose and total duration of treatment is determined by the veterinarian per individual case depending on the severity of symptoms. Following effects a list of some of the most for and less common side effects deriving from the use of prednisone in dogs.

  • REFERENCE –  1 Ciriaco et al 2013 Corticosteroid related central nervous systems side effects Journal of Pharmacology and Pharmacotherapeutics .
  • However, the major impact of Cushing’s is seen in a reduction the quality of life of dogs with the condition.
  • Some cats and dogs can be particularly susceptible to side effects of steroids, in which cases lower doses may be needed.
  • Drug doses, type or frequency may be altered in light of concerns about side effects, and other medications can be given to alleviate symptoms.

The mainstay of treating SRMA is suppression of the immune system with drugs, particularly high doses of corticosteroids like prednisolone. The administration of high doses of steroids by injection or orally very often results in significant and rapid improvement or resolution of the clinical signs. Short-term use of prednisolone is unlikely to cause adverse side effects in horses.

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The risk of hypokalaemia may be increased if prednisolone is administered together with potassium depleting diuretics. Thankfully yes and, in the long term, most dogs will be able to live a normal life. The mainstay of treating SRMA is suppression of the immune system with drugs, particularly high doses of corticosteroids like Prednisolone, to counteract the ‘over-excitation’ of the immune system.

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Treatment with steroids is normally required for 5-7 months, after which treatment can be stopped and a normal length and quality of life can be expected. Occasionally additional medications are required, such as cyclosporine and azathioprine which are given orally, either to aid suppression of the immune system, or to allow us to reduce the steroid dose without fear of relapse. With the information above, it is important to maintain perspective. Not all dogs will have side effects and steroids may be the best treatment option in certain cases.

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This is no mean feat, as it involves changing the way the body is programmed to behave towards substances which trigger reactions. Indications for use, specifying the target speciesFor the symptomatic treatment or as adjunct treatment of inflammatory and immune-mediated diseases in dogs and cats. Continue giving Prednisolone and talk to your veterinarian if your pet experiences insomnia, nausea, vomiting or stomach upset, fatigue, muscle weakness or joint pain, problems with diabetes control, or increased hunger or thirst.

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Complete blood profiles (liver function test and haematology) are recommended on a six monthly basis to monitor for the animal for potential side effects. Bromide is a much safer drug by its nature (form of salt) despite still causing increased thirst and appetite. It is absorbed, distributed within the body and excreted without interfering with the liver. Its use as a second choice therapy is attributed to the long time it takes to reach efficient blood levels (around 3 to 6 months).

If you have any concerns about the steroid treatment your pet has been prescribed it is always best to discuss this with your vet. Despite the side-effects that may be caused by steroid use, your vet will try to ensure that these won’t occur by using the lowest dose that is effective for treating your pet’s condition. However, if you do notice any of the symptoms outlined above or notice a difference in your dog’s behaviour as a result of the administration of steroids, then make sure to note them down and let your vet know as soon as possible. IBD activity index (IBDAI) scores were determined at diagnosis and after 6 weeks of treatment.